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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
32.73
Human Site:
T259
Identified Species:
55.38
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
T259
V
V
K
V
C
E
S
T
L
R
K
R
L
T
E
Chimpanzee
Pan troglodytes
XP_510208
819
88957
T401
V
V
K
V
C
E
S
T
L
R
K
R
L
T
E
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
G197
F
A
H
L
L
E
F
G
E
K
N
H
E
V
S
Dog
Lupus familis
XP_548005
637
70371
L235
E
D
T
P
T
S
Q
L
T
V
D
E
F
M
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
T259
V
V
K
V
C
E
S
T
L
R
K
R
L
T
E
Rat
Rattus norvegicus
NP_001100231
686
74096
T269
V
V
K
V
C
E
S
T
L
R
K
R
L
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
T260
V
V
K
V
C
E
S
T
L
R
K
R
L
T
E
Frog
Xenopus laevis
NP_001088063
660
73751
V253
I
K
E
V
I
R
V
V
K
V
C
E
S
T
L
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
T258
V
V
K
V
C
E
T
T
L
R
K
R
L
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
T260
V
V
K
I
H
E
S
T
L
R
K
R
L
S
E
Honey Bee
Apis mellifera
XP_623775
648
73504
T246
H
E
F
N
R
S
P
T
D
I
I
K
I
V
K
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
V254
V
V
H
I
S
E
G
V
I
R
K
R
L
D
E
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
T261
V
V
K
V
C
D
A
T
L
R
K
R
L
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
K194
E
K
L
D
L
A
D
K
K
I
K
V
V
K
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
6.6
0
N.A.
100
100
N.A.
N.A.
100
13.3
93.3
N.A.
80
6.6
53.3
80
P-Site Similarity:
100
100
20
0
N.A.
100
100
N.A.
N.A.
100
26.6
100
N.A.
93.3
26.6
66.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
8
8
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
50
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
0
8
0
8
8
0
8
0
8
0
0
8
8
% D
% Glu:
15
8
8
0
0
65
0
0
8
0
0
15
8
0
65
% E
% Phe:
8
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
8
0
15
0
8
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
8
0
0
15
8
0
0
0
8
15
8
0
8
0
0
% I
% Lys:
0
15
58
0
0
0
0
8
15
8
72
8
0
8
8
% K
% Leu:
0
0
8
8
15
0
0
8
58
0
0
0
65
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
8
0
0
0
65
0
65
0
0
8
% R
% Ser:
0
0
0
0
8
15
43
0
0
0
0
0
8
15
8
% S
% Thr:
0
0
8
0
8
0
8
65
8
0
0
0
0
50
0
% T
% Val:
65
65
0
58
0
0
8
15
0
15
0
8
8
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _